Deep, qualified next-generation sequencing has uncovered that subclonal mutations (i.e., Individuals current in only a fraction of tumor cells) could be detected for all driver genes and therefore are connected to immediate sickness development and weak consequence.eleven–thirteen This is particularly related for TP53
This selection could well be notably useful for non-compliant people or those in whom ibrutinib is contraindicated. If FCR is definitely the treatment of alternative, warning should be taken in people with NOTCH1
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れたかを表しており，円が小さいほどその地点で判別され た回数は少なくなる．グラフから，設置したビーコンの付
mutations, dropped their damaging outcome in people addressed with VO. The one element that remained predictive of the shorter development-free of charge survival Within this cohort of patients was TP53
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